Why Topologically Constrained Tetraazamacrocycles? Factors for strong binding: Molecular Organization
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چکیده
introduction, topologically constrained azamacrocycles, defined as macrocycles having additional bridges besides the basic parent ring between nitrogen atoms donors, will be discussed. Special attention will be paid to a unique class of macrocycles consisting of cross-bridged macrocyclic ligands having added components of topological and rigidity constraints. These impart exceptional kinetic and thermal stabilities to the complexes, dramatically accentuating the advantages of macrocyclic ligands, both (1) and (2) above.
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Topologically constrained manganese(III) and iron(III) complexes of two cross-bridged tetraazamacrocycles.
A family of Mn3+ and Fe3+ complexes of 4,11-dimethyl-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane (1) and 4,10-dimethyl-1,4,7,10-tetraazabicyclo[5.5.2]tetradecane (2) has been prepared by the chemical oxidation of the divalent manganese and iron analogues. The ligands are ethylene cross-bridged tetraazamacrocycles derived from cylam and cyclen, respectively. The synthesis and characterization of t...
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